DescriptionFor nearly 50 years, Sleisenger & Fordtran’s Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you’ll quickly and easily find the information you need.Key FeaturesFeatures new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more.Offers reliable coverage of key topics such as Barrett’s esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation.Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management.Employs a consistent, templated, format throughout for quick retrieval of information.Includes monthly updates online, as well as more than 20 procedural videos.Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.Table of ContentsVOLUME 1Part I: Biology of the Gastrointestinal tractCellular Growth and Neoplasia, 1 – Ezra BursteinMucosal Immunology and Inflammation, 13 – CIharles O. Elson and Phillip D. SmithThe Enteric Microbiota, 24 – Eugene B. Chang and Purna Kashyap Gut Sensory Transduction, 34 – Diego V. Bohórquez and Rodger A. LiddlePart II: Nutrition in GastroenterologyNutritional Principles and Assessment of the Gastroenterology Patient, 52 – Joel B. Mason Nutritional Management, 74 – Angela K. Pham and Stephen A. McClaveObesity, 92 – Rekha B. Kumar and Louis J. AronneSurgical and Endoscopic Treatment of Obesity, 101 – Shelby Sullivan, Steven A. Edmundowicz, and John Magaña MortonFeeding and Eating Disorders, 117 – Debra K. Katzman and Mark L. NorrisFood Allergies, 133 – J. Andrew BirdPart III: Symptoms, Signs, and Biopsychosocial IssuesAcute Abdominal Pain, 144 – Frederick H. MillhamChronic Abdominal Pain, 158 – Joseph C. Yarze and Lawrence S. Friedman Symptoms of Esophageal Disease, 168 – Kenneth R. DeVaultDyspepsia,177 – Jan TackNausea and Vomiting, 191 – Arvind Rengarajan and C. Prakash Gyawali Diarrhea, 204 – Lawrence R. Schiller and Joseph H. SellinIntestinal Gas, 224 – Fernando AzpirozFecal Incontinence, 232 – Satish S.C. RaoConstipation,250 – Johanna C. Iturrino and Anthony J. LemboGastrointestinal Bleeding, 276 – Thomas J. Savides and Dennis M. Jensen Jaundice, 313 – Steven D. LidofskyBiopsychosocial Issues in Gastroenterology, 324 – Douglas A. Drossman and Laurie KeeferFactitious Gastrointestinal Disease, 340 – John S. Fordtran and Anahit A. ZeynalyanPart IV: Topics Involving Multiple OrgansOral Diseases and Oral Manifestations of Gastrointestinal and Liver Diseases, 350 – Kimberly L. Pham and Ginat W. MirowskiCutaneous Manifestations of Gastrointestinal and Liver Diseases, 359 – Lawrence A. MarkDiverticula of the Pharynx, Esophagus, Stomach, and Small Intestine, 372 – Kerry B. Dunbar and D. Rohan Jeyarajah Abdominal Hernias and Gastric Volvulus, 381 – D. Rohan Jeyarajah and Kerry B. DunbarForeign Bodies, Bezoars, and Caustic Ingestions, 399 – Patrick R. Pfau and Mark Benson Abdominal Abscesses and Gastrointestinal Fistulas, 411 – Gregory dePrisco, Scott Celinski, and Cedric W. Spak Eosinophilic Disorders of the Gastrointestinal Tract, 424 – Marc E. Rothenberg and Vidhya Kunnathur Protein-Losing Gastroenteropathy, 435 – David A. GreenwaldGastrointestinal Lymphomas, 442 – Praveen Ramakrishnan Geethakumari and Syed Mujtaba Rizvi Gastrointestinal Stromal Tumors, 458 – Margaret von Mehren Neuroendocrine Tumors, 472 – Jonathan R. Strosberg and Taymeyah Al-ToubahGastrointestinal Consequences of Infection with Human Immunodeficiency Virus, 498 – C. Mel WilcoxGastrointestinal and Hepatic Complications of Solid Organ and Hematopoietic Cell Transplantation, 510 – Anne M. Larson, Rachel B. Issaka, and David M. HockenberyGastrointestinal and Hepatic Manifestations of Systemic Diseases, 532 – Frederick WeberVascular Lesions of the Gastrointestinal Tract, 561 – Joann Kwah and Lawrence J. Brandt Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm, 580 – Jeffrey B. Matthews and Kiran TuragaGastrointestinal and Hepatic Disorders in the Pregnant Patient, 593 – Shilpa Mehra and John F. Reinus Acute and Chronic Gastrointestinal Side Effects of Radiation Therapy, 606 – Jarred P. Tanksley, Christopher G. Willett, Brian G. Czito, and Manisha PaltaPreparation for and Complications of Gastrointestinal Endoscopy, 619 – Aravind Sugumar and John J. Vargo IIPart V: EsophagusAnatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus,627 – Ryan D. Madanick and Vishal KailaEsophageal Neuromuscular Function and Motility Disorders, 638 – John E. Pandolfino and Peter J. KahrilasEsophageal Disorders Caused by Medications, Trauma, and Infection, 661 – David A. Katzka Gastroesophageal Reflux Disease, 670 – Joel E. Richter and Michael F. VaeziBarrett Esophagus, 691 – Stuart Jon Spechler and Rhonda F. SouzaEsophageal Tumors, 700 – Hazem Hammad and Sachin WaniPart VI: Stomach and DuodenumAnatomy, Histology and Developmental Anomalies of the Stomach and Duodenum, 720 – M. Gaith Semrin Gastric Neuromuscular Function and Neuromuscular Disorders, 735 – Kenneth L. Koch Gastric Secretion,764 – Mitchell L. Schubert and Jonathan D. Kaunitz52 Gastritis and Gastropathy, 781 Mark Feldman, Pamela J. Jensen, and Colin W. HowdenPeptic Ulcer Disease, 806 – Francis K.L. Chan and James Y.W. Lau Adenocarcinoma of the Stomach and Other Gastric Tumors, 820 – Michael Quante and Jan BornscheinPart VII: PancreasAnatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas, 842 – Megha S. Mehta, Bradley A. Barth, and Sohail Z. Husain Pancreatic Secretion, 853 – Stephen J. PandolGenetic Disorders of the Pancreas and Pancreatic Disorders in Childhood, 862 – David C. Whitcomb and Mark E. Lowe Acute Pancreatitis, 893 – Santhi Swaroop Vege Chronic Pancreatitis, 917 – Chris E. Forsmark Pancreatic Cancer, Cystic Pancreatic Neoplasms, and Other Nonendocrine Pancreatic Tumors, 947 – Bijal Modi and G. Thomas Shires Endoscopic Treatment of Pancreatic Disease, 965 – Ryan Law and Todd H. BaronPart VIII: Biliary tractAnatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract, 973 – Frederick J. Suchy and Cara L. MackBiliary Tract Motor Function and Dysfunction, 995 – B. Joseph Elmunzer and Grace H. EltaBile Secretion and the Enterohepatic Circulation, 1001 – Peter Fickert and Paul A. DawsonGallstone Disease, 1016 – David Q.-H. Wang and Nezam H. AfdhalTreatment of Gallstone Disease, 1047 – Robert E. GlasgowAcalculous Biliary Pain, Acute Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Gallbladder Polyps, 1064 – Karin L. Andersson and Lawrence S. Friedman Primary and Secondary Sclerosing Cholangitis, 1077 – Cynthia Levy and Christopher L. BowlusTumors of the Bile Ducts, Gallbladder, and Ampulla, 1096 – Sumera H. Rizvi and Gregory J. GoresEndoscopic and Radiologic Treatment of Biliary Disease, 1113 – Theodore W. James and Todd H. BaronVOLUME 2 Part IX: LiverEmbryology, Anatomy, Histology, and Developmental Anomalies of the Liver,1129 – Ricard Masia and Joseph MisdrajiLiver Physiology and Energy Metabolism, 1135 – Namita Roy-Chowdhury and Jayanta Roy-ChowdhuryLiver Chemistry and Function Tests, 1154 – Daniel S. PrattOverview of Cirrhosis, 1164 – Patrick S. Kamath and Vijay H. Shah Hemochromatosis, 1172 – Bruce R. Bacon and Robert E. Fleming Wilson Disease, 1180 – Eve A. RobertsOther Inherited Metabolic Disorders of the Liver, 1189 – James E. Squires and William F. Balistreri Hepatitis A, 1210 – Maria H. Sjogren and Joseph G. Cheatham Hepatitis B, 1216 – Harry L.A. Janssen and Scott FungHepatitis C, 1243 – Jacinta A. Holmes and Raymond T. Chung Hepatitis D, 1283 – Marc G. GhanyHepatitis E, 1292 – Rakesh AggarwalHepatitis Caused by Other Viruses, 1298 – Jordan J. FeldBacterial, Parasitic, and Fungal Infections of the Liver, Including Liver Abscesses, 1303 – Arthur Y. Kim and Raymond T. Chung Vascular Diseases of the Liver, 1321 – Filipe Gaio Nery and Dominique Charles VallaAlcohol-Associated Liver Disease, 1336 – Gyongyi Szabo and Craig J. McClainNonalcoholic Fatty Liver Disease, 1354 – Dawn M. Torres and Stephen A. HarrisonLiver Disease Caused by Drugs, 1367 – Shivakumar Chitturi, Narci C. Teoh, and Geoffrey C. Farrell Liver Disease Caused by Anesthetics, Chemicals, Toxins, and Herbal and Dietary Supplements, 1399 – James H. Lewis Autoimmune Hepatitis, 1415 – Albert J. CzajaPrimary Biliary Cholangitis, 1433 – John E. Eaton and Keith D. Lindor Portal Hypertension and Variceal Bleeding, 1443 – Vijay H. Shah and Patrick S. KamathAscites and Spontaneous Bacterial Peritonitis, 1471 – Elsa Solà and Pere Ginès Hepatic Encephalopathy, Hepatorenal Syndrome, Hepatopulmonary Syndrome, and Other Systemic Complications of Liver Disease, 1486 – Shivang S. Mehta and Michael B. Fallon Acute Liver Failure, 1499 – John O’Grady and William Bernal Hepatic Tumors and Cysts, 1509 – Adrian M. Di Bisceglie and Alex S. Befeler Liver Transplantation, 1533 – Andres F. Carrion and Paul MartinPart X: Small and Large IntestineAnatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine, 1551 – Lee M. Bass and Barry K. WershilSmall Intestinal Motor and Sensory Function and Dysfunction, 1580 – Christopher K. Rayner and Patrick A. Hughes Colonic Motor and Sensory Function and Dysfunction, 1595 – Philip G. Dinning, Marcello Costa, and Simon J.H. Brookes Intestinal Electrolyte Absorption and Secretion, 1611 – Mrinalini C. Rao and Jayashree Sarathy Digestion and Absorption of Carbohydrate, Protein, and Fat, 1636 – Yangzom D. Bhutia and Vadivel Ganapathy Digestion and Absorption of Micronutrients, 1657 – Michelle Pearlman and Jaime Almandoz Maldigestion and Malabsorption, 1677 – Christoph Höegenauer and Heinz F. HammerSmall Intestinal Bacterial Overgrowth, 1711 – Brian E. Lacy and John K. DiBaise Short Bowel Syndrome, 1720 – Alan L. Buchman Celiac Disease, 1736 – Benjamin Lebwohl and Peter H.R. GreenTropical Diarrhea and Malabsorption, 1756 – Balakrishnan S. Ramakrishna Whipple Disease, 1769 – Matthias Maiwald, Axel von Herbay, and David A. RelmanInfectious Enteritis and Proctocolitis, 1779 – Joanna M.P. Melia and Cynthia L. SearsFood Poisoning, 1810 – Jennifer KatzAntibiotic-Associated Diarrhea and Clostridioides difficile Infection, 1818 – Ciarán P. Kelly and Sahil Khanna Intestinal Protozoa, 1834 – Christopher D. Huston Intestinal Worms, 1847 – M. Nedim Ince and David E. Elliott Epidemiology, Pathogenesis, and Diagnosis of Inflammatory Bowel Diseases, 1868 – Gilaad G. Kaplan and Siew C. NgManagement of Inflammatory Bowel Diseases, 1898 – Ashwin N. Ananthakrishnan and Miguel D. RegueiroIleostomies, Colostomies, Pouches, and Anastomoses, 1930 – Ahsan Raza and Farshid AraghizadehIntestinal Ischemia, 1944 – Paul Feuerstadt and Lawrence J. BrandtIntestinal Ulcerations, 1970 – Blair Lewis and Daniel S. MishkinAppendicitis,1983 – Martin Daniel Rosenthal and George S. Sarosi, Jr.Diverticular Disease of the Colon, 1993 – Taft P. Bhuket and Neil H. StollmanIrritable Bowel Syndrome, 2008 – Alexander C. Ford and Nicholas J. Talley Intestinal Obstruction, 2021 – William Conan Mustain and Richard H. TurnageIleus and Pseudo-Obstruction Syndromes, 2039 – Adil E. Bharucha and David O. PrichardTumors of the Small Intestine, 2059 – Boris Blechacz and Robert Scott BresalierColonic Polyps and Polyposis Syndromes, 2076 – John J. Garber and Daniel C. ChungJohn J. Garber and Daniel C. Chung Colorectal Cancer, 2108 – Robert Scott BresalierOther Diseases of the Colon, 2153 – Darrell S. Pardi and Thomas G. Cotter Anal Diseases, 2169 – J. Marcus Downs and Benjamin KulowPart XI: Additional Treatments for Patients with Gastrointestinal and Liver DiseaseProbiotics, 2187 – Eamonn M.M. Quigley Complementary, Alternative, and Integrative Medicine, 2192 – Jill K. Deutsch and David J. HassPalliative Care Medicine in Patients with Advanced Gastrointestinal and Hepatic Disease, 2206 – Vyjeyanthi S. Periyakoil, Nielsen Fernandez-Becker, and Sarah E. StreettAuthor InformationBy Mark Feldman, MD, William O. Tschumy Jr., MD, Chair of Internal Medicine, Director, Internal Medicine Residency Program, Texas Health Presbyterian Hospital Dallas; Clinical Professor of Internal Medicine, University of Texas Southwestern Medical School, Dallas, TexasLawrence S. Friedman, MD, Professor of Medicine, Harvard Medical School; Professor of Medicine, Tufts University School of Medicine, Boston, Massachusetts; The Anton R. Fried, MD, Chair, Department of Medicine, Newton-Wellesley Hospital, Newton, Massachusetts; Assistant Chief of Medicine, Massachusetts General Hospital, Boston, MassachusettsLawrence J. Brandt, MD, Professor of Medicine and Surgery, Albert Einstein College of Medicine, Emeritus Chief, Division of Gastroenterology, Montefiore Medical Center, Bronx, New York
